We'll be at the Parkinson's Disease Therapeutics Conference 2015, sponsored by Michael J. Fox Foundation for Parkinson's Research November 3rd. Hope to see you at the Conference.

Sharp Edge Labs
Sharp Edge Labs shared Alzheimer's Drug Discovery Foundation's post.Thursday, February 11th, 2016 at 10:49am
An important study showing that knowledge is power (power to change).
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Sharp Edge Labs
Sharp Edge LabsFriday, February 5th, 2016 at 10:02am
Company Founder Marcel Bruchez just published a new work in Nature Methods in using the biosensor technology for targeted photosensitization in-vivo. Very cool stuff, and a whole new direction for the technology.

http://www.nature.com/nmeth/journal/vaop/ncurrent/full/nmeth.3735.html
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Sharp Edge Labs
Sharp Edge LabsMonday, February 1st, 2016 at 1:05am
Company founders Alan Waggoner and Marcel Bruchez are interviewed by the Pittsburgh Post Gazette on creating the technology that drives discovery at Sharp Edge Labs.
http://www.post-gazette.com/video/?v=4693303072001
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Sharp Edge Labs
Sharp Edge LabsWednesday, January 6th, 2016 at 11:19am
We'll be at the Biotech Showcase happening during the J.P. Morgan Biotech conference next week (Jan. 11-13). We're meeting with partners, potential investors, and many colleagues and old friends.

It's generally pretty wall-to-wall with meetings, but it is THE place to be in January, in our industry!
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Off the Shelf
  • hERG Trafficking
    hERG Ion Channel Trafficking, another mechanism of hERG inhibition, and a standard test for chemical chaperones such as those used in CFTR research.
  • PgP(G268V) Trafficking
    Mutant PgP (G268V) trafficking assays available for studying CFTR corrector selectivity.
  • Cystic Fibrosis: CFTR Trafficking
    CFTR wild-type and deltaF508 mutant trafficking assays available.
  • Trafficking & Internalization Assays
    Studying GPCRs, Ion Channels or Transporters? Get a deeper understanding of trafficking as a new pharmacological mechanism for these key targets.
  • The Sharp Edge Dyes
    Sharp Edge provides high-quality dyes for it's partners. Learn more about the dyes and how to handle them here.
  • pH Sensors
    Useful for tracking surface-protein endocytosis, we're preparing a new class of targeted pH Sensors.
On the Bench
  • Lysosomal Storage Disorders: Trafficking Assays
    Trafficking to the lysosome is a key defect in lysosomal storage disorders. Our trafficking assays provide a direct measure of restored trafficking, providing the opportunity to discover entirely new compound classes.
  • Immunosensors (SBIR)
    We're developing a new set of proprietary add-and-read biosensors under an SBIR Phase I grant from NCI.
  • FAP-Capture
    With your protein FAP-tagged, you can use these reagents for capture and quantification.
Sharp Edge Radar